Presentation 4

Aiming to extend healthy life span by eliminating senescent cells


Nakanishi Makoto

Professor, Division of Cancer Cell Biology,
The Institute of Medical Science, The University of Tokyo

After graduating from Nagoya City University School of Medicine in 1985 and obtaining the medical license, he entered the Department of Biochemistry at Nagoya City University Graduate School of Medicine, where he conducted research on digestive enzymes in the liver and was awarded the title of Doctor of Medicine in 1989. In April 1989, he joined the Department of Biochemistry, Jichi Medical School as an Assistant Professor, and in 1992 became a Lecturer in the same department. His research during this period was on amino acid transport. He then studied at Baylor College of Medicine in the U.S. from 1993 to 1995, where he began my research on cellular senescence. In 1997, he became Director of the Department of Geriatric Disease of the National Institute for Longevity Sciences. In 2000, he became Professor at Nagoya City University School of Medicine. In 2016, he became Professor at the Institute of Medical Science, University of Tokyo and Deputy Dean of the institute (from 2019). Since his study abroad, he has consistently conducted research on induction of cellular senescence and individual aging by DNA damage response.